PolyPhil™ Polynucleotides
Beauty Needs No Filter — skin quality, refined from within.
Overview
PolyPhil™ is Croma’s injectable polynucleotide range designed to improve skin quality from within, supporting hydration, elasticity, firmness, texture, and overall radiance.
Powered by PN-HPT™ (Polynucleotides High Purification Technology), PolyPhil™ works by supporting fibroblast activity, collagen synthesis, hydration, and antioxidant activity. The result is not about changing the face; it is about restoring healthier, fresher, more resilient skin.
What It Delivers
– Improved skin hydration
– Better skin texture and elasticity
– Reduction in fine lines
– Skin radiance and glow
– Support for acne scars and striae protocols
– Skin preparation before other aesthetic procedures
PolyPhil™ can be used as a standalone treatment or as part of the Skin Enhancement Technique (SET), helping prepare the skin before treatments such as lasers, energy-based devices, fillers, peeling, needling, and surgery.
Technology
Powered by PN-HPT™ (Polynucleotides High Purification Technology), PolyPhil™ uses polynucleotides derived from fresh-water trout raised in controlled European fish farms, ensuring:
– Strict veterinary, water, and food control
– Heavy-metal contamination control
– Full traceability throughout the fish life cycle
– A consistently safe and reliable raw material
The result is a highly purified polynucleotide that supports fibroblast activity, collagen synthesis, hydration, and antioxidant activity in the skin.
Portfolio
PolyPhil™
Core skin quality booster for face, body, scalp, and hands. PN-HPT™ 40 mg / 2 ml.
PolyPhil™ Eye
Dedicated support for the eye contour, eyelids, and delicate areas. PN-HPT™ 15 mg / 2 ml.
PolyPhil™ Hair
Scalp and eyebrow protocols, including pre and post hair restoration. PN-HPT™ 15 mg / 2 ml.
PolyPhil™ Next
Mature and dehydrated skin support with hydration boost. PN-HPT™ 20 mg + HA 20 mg + mannitol.
Why PolyPhil™
– Fresh-water trout-derived polynucleotides
– Controlled European fish-farm sourcing
– PN-HPT™ High Purification Technology
– Supports hydration, collagen synthesis, fibroblast activity, and scavenging activity
– Suitable as standalone treatment or SET protocol
– Portfolio options for face, body, eye area, hair, and dehydrated skin
– 91% clinical improvement in superficial fine lines and skin quality
FAQ
What are polynucleotides?
Polynucleotides are DNA-based biopolymers used in aesthetic medicine to support the skin’s natural regenerative processes, including hydration, collagen production, tissue quality, and repair.
Is PolyPhil™ a filler?
No. PolyPhil™ is not designed to create volume like a dermal filler. It is a skin quality treatment that supports hydration, elasticity, texture, and radiance.
Can PolyPhil™ be combined with other treatments?
Yes. It can be used as part of SET to prepare and enhance the skin before or alongside lasers, energy devices, fillers, peeling, needling, and surgery.
Which PolyPhil™ is best for the eye area?
PolyPhil™ Eye is the dedicated option for the eye contour, eyelids, and delicate areas.
Which PolyPhil™ is best for mature or dehydrated skin?
PolyPhil™ Next combines PN-HPT™, non-crosslinked hyaluronic acid, and mannitol for hydration and skin quality support.
Which PolyPhil™ is used for hair?
PolyPhil™ Hair is designed for scalp and eyebrow protocols.