Genefill DX™
The Triple Effect Hybrid Technology. Instant lift. Long-term regeneration.
Overview
Genefill DX™ is a next-generation hybrid dermal filler engineered to do more than simply add volume. It combines cross-linked hyaluronic acid for immediate lift, hydration, and structure with Dextranomer microspheres for fibroblast activation, collagen stimulation, and dermal regeneration.
This dual mechanism delivers what most fillers cannot achieve alone: instant contouring, regenerative biostimulation, and long-term skin remodeling.
What It Delivers
– 2-3x faster regenerative response
– Strong stimulation of collagen types I, III, IV and VI
– Increased elastin for better elasticity and recoil
– Improved tissue architecture through ECM remodeling
– Natural-looking integration in dynamic facial zones
– High patient satisfaction
– Strong safety profile with very low adverse event rates
Ideal for cheeks, nasolabial folds, marionette lines, jawline, and chin, where structural contouring meets regenerative benefit.
Technology
Genefill DX™ combines two active components working in synergy:
– Cross-linked HA (14 mg/ml): immediate volume, lift, hydration, and contour definition
– Dextranomer (50 mg/ml): biocompatible microspheres that activate fibroblasts and stimulate collagen, elastin, and ECM remodeling
Both are delivered through Croma’s proprietary platform:
– ATT® (Advanced Thixotropic Technology) for smoother extrusion and homogeneous placement
– CRM® (Covalent Reticulated Matrix) for durability, elasticity, and longevity
The result is a single syringe that performs as both a filler and a biostimulator: immediate visible correction plus long-term regenerative outcomes.
Triple Effect
1. Immediate Volume
Cross-linked HA creates contour, lift, projection, and structure. Immediate visible result.
2. Biostimulation
Dextranomer activates fibroblasts and stimulates collagen types I, III, IV, VI and elastin. Long-term firmness and density.
3. Regeneration
Dermal matrix remodeling improves tissue repair, elasticity, skin quality, firmness, and structural integrity.
Why Genefill DX™
– Immediate filler result, biostimulator benefit, and regenerative outcome in one product
– Natural movement with long-lasting correction
– Hydration, collagen support, elastin support, and tissue repair
– Stimulates collagen types I, III, IV and VI plus elastin
– One syringe doing the work of two product categories
– Reversible thanks to the HA component
– Strong safety profile with very low adverse event rates
FAQ
Is Genefill DX a filler or a biostimulator?
Both. It is a hybrid filler-biostimulator. Immediate HA effect plus long-term regenerative stimulation.
What makes it different from regular HA filler?
Regular HA provides mostly volume. Genefill DX provides volume plus collagen, elastin, and regeneration.
How long does it last?
Up to 12 months, depending on indication and metabolism.
Is it reversible?
Yes. Because of the HA component, hyaluronidase reversibility is part of the platform advantage.
Who is the ideal patient?
Patients wanting contour, lift, structure, collagen stimulation, natural results, and long-term skin improvement.